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Damian Nowak – Adam Bachorz – Professor Marcin Hoffmann | Using Machine Learning to Discover New Medicines

Damian Nowak – Adam Bachorz – Professor Marcin Hoffmann | Using Machine Learning to Discover New Medicines

Many researchers today are dedicated to the discovery of new medicines. Over the past few decades, their tireless efforts have culminated in a database of around 100 million known drug molecules. This value may already sound vast, but by current estimates, the true number of small drug-like molecules could actually range anywhere between 1023 – already more than the number of grains of sand on Earth – and 1060 – comparable to the number of atoms in an entire galaxy. With existing approaches, researchers ultimately need to test the medical potential of these molecules individually, taking up vast amounts of time and computing power.

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Dr Martin Van Den Berghe | Combatting Climate Change with Microbe-Enhanced Rock Weathering

Dr Martin Van Den Berghe | Combatting Climate Change with Microbe-Enhanced Rock Weathering

In the fight against climate change, carbon capture and storage technologies are widely seen as a critical tool in avoiding the worst effects of global warming. The problem is being approached from many different angles, but many proposed solutions have a long way to go before they can have any meaningful impact on the health of Earth’s climate. According to Dr Martin Van Den Berghe at Cytochrome Technologies, one of the most promising approaches to carbon capture could be to enhance a chemical mechanism that has naturally shaped Earth’s geology for billions of years.

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Dr Alvin Orbaek White | Advancing Energy Technologies with Ultralong Carbon Nanotubes

Dr Alvin Orbaek White | Advancing Energy Technologies with Ultralong Carbon Nanotubes

Carbon nanotubes are a unique family of molecules that look like tiny carbon tunnels with honeycomb walls. They are typically around 1 nanometre in diameter and several nanometres long. In principle, carbon nanotubes are much more efficient at conducting electricity than metals, especially since they are so lightweight and have high-temperature stability compared to metals. So far, however, their full potential has been limited by the techniques used to manufacture them.

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Dr Aaron Tallman | Assessing Uncertainties When Measuring 3D Printed Metal Parts

Dr Aaron Tallman | Assessing Uncertainties When Measuring 3D Printed Metal Parts

The ability to 3D print metal parts presents exciting opportunities to simplify the designs of many advanced technologies, and improve their performance. However, on microscopic scales, printed metals can have defects that cause their mechanical properties to vary unpredictably, lowering the quality of final products. To assess these variations, researchers use a technique named profilometry-based indentation plastometry, or PIP. This technique involves pressing a hard tip into a material on a flat surface, and then scanning a probe across the crater to measure the shape left behind.

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Dr Yujeong Bae | Advancing Scanning Tunnelling Microscopy for Quantum Information Processing

Dr Yujeong Bae | Advancing Scanning Tunnelling Microscopy for Quantum Information Processing

The ability to manipulate single atoms and molecules would transform how we store and process digital information. This can be achieved using a cutting-edge technique named scanning tunnelling microscopy. Scanning tunnelling microscopes (STMs) are powerful imaging devices, which operate by holding a sharp metal tip less than one nanometre above a conducting sample. Through the effects of quantum tunnelling, electrons can pass through the tiny vacuum gap between the tip and the sample surface.

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Sabine Grüner-Lempart – Julian Eckert | Removing Industrial Pollution with Bacteria

Sabine Grüner-Lempart – Julian Eckert | Removing Industrial Pollution with Bacteria

Harmful chemicals are commonplace in many different industries. Volatile organic compounds – or ‘VOCs’ – represent one such type of chemicals, which are particularly prevalent in industries that require spraying of paints and coatings. Unfortunately, VOCs can readily evaporate into the air, potentially harming people’s health through inhalation. Some VOCs are also environmental pollutants and can even contribute to climate change.

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How Interconnected Bubbles Affect the Bread-Making Process – How Interconnected Bubbles Affect the Bread-Making Process

How Interconnected Bubbles Affect the Bread-Making Process – How Interconnected Bubbles Affect the Bread-Making Process

Bread is a vital source of nutrition for billions of people, and its demand is now rising even in regions where wheat doesn’t grow naturally. Wheat is the only grain that can produce high-quality bakery products. For farmers, in addition to facing the challenges of growing high-yield, high-protein wheat, they also need flour to be strong for baking, making good-quality, large loaves. Loaf size and crumb quality are strongly tied to the growth of gas bubbles inside the rising dough. So far, it has been difficult to predict the dynamics of bubbles in doughs from the properties of unprocessed flours.

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Professor Zhiliang Zhang | The Super-tough Coating that Repels Ice

Professor Zhiliang Zhang | The Super-tough Coating that Repels Ice

Ice can cause serious damage to vehicles and infrastructure, including aircraft, pavements, power lines, and wind turbines. It is important to remove ice before it causes damage, but doing this manually is often expensive and energy-intensive, and sometimes even dangerous. Researchers have begun to develop so-called ‘super-hydrophobic’ coatings, which can repel incoming water droplets before they freeze. This not only prevents ice from building up; it also weakens the adhesion of ice that does freeze to the surface, allowing it be removed more easily.

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Dr Francesco Muia | Unlocking the Universe’s Secrets with Ultra-high-frequency Gravitational Waves

Dr Francesco Muia | Unlocking the Universe’s Secrets with Ultra-high-frequency Gravitational Waves

In the early 1900s, Einstein revolutionized our understanding of space and time, revealing them as interconnected aspects of the universe’s fabric – known as ‘spacetime’. Spacetime isn’t a rigid background. Like a ball on a trampoline, heavy objects like the Sun warp spacetime around them, drawing the planets into orbits. When heavy objects move extremely fast – such as when two black holes orbit each other and merge or in highly energetic events like those occurring in the early universe – the warping becomes extreme, generating waves that spread through spacetime. These ‘gravitational waves’, first discovered in 2015, offer scientists new tools to explore the universe.

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Dr Kei Toyota | A New Way to Create Conductive Polymers for Technological Applications

Dr Kei Toyota | A New Way to Create Conductive Polymers for Technological Applications

Polymers, made from incredibly long chains of smaller molecules, make up many materials used in the modern world. From simple plastics to medical devices and solar cells, polymers represent a diverse and exciting area of science. The majority of polymers are made from carbon-based molecules. Perhaps even more fascinating are hybrid polymers, which are composed of both carbon-based and metal-based components. Hybrid polymers have unique properties, such as conductivity, making them especially desirable for new technologies. Dr Kei Toyota at the Panasonic Corporation in Osaka, Japan, has been investigating new ways to develop hybrid polymers.

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Dr Egle Tomasi-Gustafsson | Dr Simone Pacetti – Probing the Proton: Understanding the Structure of Sub-Atomic Particles

Dr Egle Tomasi-Gustafsson | Dr Simone Pacetti – Probing the Proton: Understanding the Structure of Sub-Atomic Particles

The world around us is made up of atoms, which we can break down into smaller sub-atomic particles. Protons are positively charged sub-atomic particles – made up of three fundamental particles called ‘quarks’. Quarks are one of the building blocks of matter, and different combinations of them make up different sub-atomic particles. The proton has two ‘up’ quarks and one ‘down’ quark, which have different masses and charges. However, when we add up the masses of these three individual quarks, we get a lighter mass than the mass of a proton. So, what else is contributing to the proton’s mass?

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