Professor De’Broski Herbert | Scratching the Surface: The Role of Itch-Sensing Neurons in Fighting Parasitic Worms

Nov 20, 2024 | biology, health and medicine

About this episode

Parasitic worms cause serious health issues in billions of people worldwide, so understanding how our bodies fight them off is crucial for developing better treatments. In a new study, Professor De’Broski Herbert and his team at the University of Pennsylvania have uncovered a surprising connection between the neurons that make us itch and our body’s ability to protect itself from skin-penetrating worms. In their study, the team led by postdoctoral researcher Juan Inclan Rico, explored a subtype of sensory nerves that express a specific receptor, which can make us feel itchy in response to certain chemicals. Read More

Original Article Reference

Summary of the paper ‘MrgprA3 neurons drive cutaneous immunity against helminths through selective control of myeloid-derived IL-33’, in Nature Immunology, doi.org/10.1038/s41590-024-01982-y

Contact

For further information, you can connect with Professor De’Broski R. Herbert at debroski@vet.upenn.edu

W: https://drherbertlab.org/  

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