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Dr Yong Cheng | New Insights into How Blood Cells are Produced
During the production of new blood cells, stem cells first develop into progenitor cells. These progenitor cells undergo further rounds of differentiation to produce different types of blood cells. Each type of blood cell has a different function. For example, red blood cells transport oxygen around the blood, whereas various types of white blood cells play different roles in fighting infection. However, overactive white blood cells also play a role in auto-immune conditions, such as lupus and rheumatoid arthritis. As such, scientists are trying to better understand how blood cells develop, to find new ways of treating these conditions.
Understanding ALK+ Lung Cancer
If you have recently been diagnosed with ALK+ lung cancer, you likely have many questions. This short animation will discuss what ALK+ lung cancer is, common symptoms, and some commonly prescribed treatments. We will also include information for carers of those with ALK+ lung cancer and discuss the value of other forms of support, such as attending support groups, and making lifestyle choices that can help you to maintain physical and mental wellbeing.
Prof. Christian Bréchot | A New Therapeutic Avenue for Alzheimer’s and Diabetic Neuropathy
Many diseases can emerge as we age, with metabolic disorders such as diabetes, and neurodegenerative conditions, such as Alzheimer’s disease, representing two reasonably common age-related illnesses. Many age-related diseases share common underlying mechanisms, including inflammation, a build-up of reactive oxygen molecules that can damage cellular components, and insulin insensitivity. Treatments that can target these mechanisms could have transformational effects on age-related diseases.
Empowering Families with FRAIT: A Transformative Public Health Tool
Family resilience is the ability of a family to respond positively to an adverse situation, and emerge from the situation feeling strengthened, more resourceful and more confident than its prior state. The family is seen as a unit, and resilience refers to the family itself rather than the individual members. Families can be confronted with a multitude of challenges at any time. Those with newborn babies and young children are particularly vulnerable to stress. In the face of economic hardship, health crises, and other unforeseen adversities, it is remarkable to see families harnessing their resilience.
Professor Adèle Ehongo – Dr Noélie Bacq | Shedding Light on PICC: A Condition Associated with Visual Defects in People with Short-sightedness
Peripapillary intra-choroidal cavitation – or PICC – is a lesion that occurs at the back of the eye. This lesion is much more common in people with short-sightedness. PICC lesions occur around an area called the optic disc, where the optic nerve leaves the eyeball. While PICC is considered benign, it is frequently associated with visual defects resembling those seen in glaucoma, leading to diagnostic confusion. There is a need to better understand the condition to chart a path forward. Professor Adèle Ehongo and Dr Noélie Bacq of Erasmus Hospital in Brussels have written a review covering the latest data on PICC. Their goal is to pave the way for a greater understanding of PICC and its associated changes, to aid the development of new treatments.
Dr Xavier Alameda-Pineda | Evaluating the Potential of Social Robots in Geriatric Healthcare
Social robots will become increasingly widespread in the coming decades. So far, they have only been introduced in a few real-world environments, including some airports, museums, and hospitals. Dr Xavier Alameda-Pineda at Inria, the French National Institute for Research in Digital Science and Technology, and all the partners of the Horizon 2020 SPRING project recently set out to evaluate the potential of social robots in the context of geriatric healthcare.
Professor Anne Herrmann-Werner – Dr Teresa Festl-Wietek | An Innovative Approach to Medical Education Developed During the Pandemic
COVID-19 changed the world as we know it. Overnight, we needed to adapt to socially-distanced, online workplaces, schools and pastimes. Medical education was particularly affected by this; students were sent into virtual learning environments, while being prematurely thrust into frightening clinical settings to support frontline workers. This was problematic, given that medical students are already prone to psychological stress and above-average rates of mental disorders. However, it offered an opportunity to develop and embed innovative digital teaching concepts.
Dr. Clare Jensen – Dr. Maggie O’Haire | Can Dogs Improve the Mental Wellbeing of Pediatric Healthcare Professionals?
Interacting with therapy dogs can have significant benefits for patients, such as reduced anxiety and pain. A growing number of pediatric healthcare facilities even have ‘facility dogs’, or full-time therapy dogs who are specially trained to work closely with staff. The positive impacts of these dogs on the wellbeing of pediatric patients are well documented. However, Dr. Clare Jensen, Dr. Maggie O’Haire, and their colleagues from Purdue University and the University of Arizona wished to investigate whether facility dogs also benefit pediatric healthcare workers. Professionals in these positions are at risk of experiencing poor mental health and burnout, so finding ways to reduce their stress would be invaluable.
Dr Yong Cheng | New Insights into How Blood Cells are Produced
During the production of new blood cells, stem cells first develop into progenitor cells. These progenitor cells undergo further rounds of differentiation to produce different types of blood cells. Each type of blood cell has a different function. For example, red blood cells transport oxygen around the blood, whereas various types of white blood cells play different roles in fighting infection. However, overactive white blood cells also play a role in auto-immune conditions, such as lupus and rheumatoid arthritis. As such, scientists are trying to better understand how blood cells develop, to find new ways of treating these conditions.
The T1DRA Study: Screening Adults for Type 1 Diabetes
Type 1 diabetes is an autoimmune condition where the immune system attacks and destroys pancreatic cells that produce insulin. Near to diagnosis, people cannot produce enough insulin, meaning that their blood sugar levels can become dangerously high. Some people associate type 1 diabetes with children, but more than half of type 1 diabetes patients are diagnosed in adulthood. Researchers know very little about how the condition develops in adults. The Type 1 Diabetes Risk in Adults – or ‘T1DRA’ – Study is actively screening adults through a small blood sample to determine their risk of type 1 diabetes.
Dr. Matthew Sherrer | The Infinite Game: Changing an Adversarial Mindset in Anesthesia and Beyond
Anesthesia in the US is commonly delivered by physician anesthesiologists who medically direct certified registered nurse anesthetists in a collaborative care team model. However, in over 20 states, there is no requirement for nurse anesthetists to be medically directed, allowing them to work independently. This has resulted in a bitter turf war over the rights and responsibilities of physicians and advanced practice nurses, leading to a toxic working environment. This mindset can be compared with a ‘finite game’, where there are clear winners and losers. Unfortunately, the patient is the ultimate loser.
Dr Mary Hornick – Dr Ashley Stefanski | Exploring the Potential of Hallucinogens for Treating Opioid Use Disorder
Opioid use disorder has been on the rise in the USA, fueled by an increased availability of fentanyl and other opioids. Current gold-standard treatments involve using opioid agonist drugs, such as methadone or buprenorphine alone or in combination with opioid antagonists, to address cravings and withdrawal. However, these treatments suffer from high levels of patient relapse and can pose safety risks. A promising alternative lies in using hallucinogenic compounds that can enable ‘neuroplasticity’, which means changing the brain’s neural architecture, potentially allowing patients to overcome their addictive behaviors.
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