Dr Youzhong Guo | Accelerating Our Understanding of Cell Membranes

Aug 9, 2023 | biology

About this episode

Cell membranes are an essential constituent of all living organisms. They protect and organize cells, and perform a range of vital functions that ensure an organism’s survival. The two fundamental components of cell membranes are proteins and lipids, which form a diverse and complex system connecting the membrane to the wider cell. Interactions between cell-membrane proteins and between proteins and lipids play vital roles in myriad biological processes. Understanding these interactions is critical for identifying the mechanisms behind many medical disorders, in order to find ways of treating them. In-depth knowledge of these interactions is also crucial for drug design. Read More

Original Article Reference

Summary of the papers: ‘Detergent-free systems for structural studies of membrane proteins’, doi.org/10.1042/BST20201080; ‘A native cell membrane nanoparticles system allows for high-quality functional proteoliposome reconstitution’, doi.org/10.1016/j.bbadva.2021.100011; and ‘Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis’, doi.org/10.3791/61298

Contact

For further information, you can connect with Dr Youzhong Guo at yguo4@vcu.edu

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