Dr Rogier Hopstaken | A Simple Point-of-Care Test to Combat Antibiotic Resistance

Feb 7, 2024 | health and medicine

About this episode

While antibiotics are an essential tool for treating disease, their effectiveness in preventing severe illness and death is under threat. Antibiotic resistance is now one of the biggest dangers to global health. When a bacterial infection is treated with antibiotics, certain bacteria in a patient may hold genetic mutations that allow them to evade destruction. These resistant bacteria can become more severe and spread further, requiring stronger antibiotics or potentially leading to the patient’s death. Around 5 million deaths were related to antibiotic resistance in 2019 alone, and cases are predicted to rise. Read More

Original Article Reference

Summary of the papers:

Implementing point-of-care CRP testing for better diagnosis of acute respiratory infections, doi.org/10.3399/bjgp22X718517

Effect of C reactive protein point-of-care testing on antibiotic prescribing for lower respiratory tract infections in nursing home residents: cluster randomised controlled trial, doi.org/10.1136/bmj.n2198

Point-of-care C-reactive protein testing and antibiotic prescribing for respiratory tract infections: a randomized controlled trial, doi.org/10.1370/afm.1090

Effect of point of care testing for C-reactive protein and training in communication skills on antibiotic use in lower respiratory tract infections: cluster randomised trial, doi.org/10.1136/bmj.b1374

Contributions of symptoms, signs, erythrocyte sedimentation rate, and C-reactive protein to a diagnosis of pneumonia in acute lower respiratory tract infection, PMID: 12830562; PMCID: PMC1314594

Guidance on C-reactive protein point-of-care testing and complementary strategies to improve antibiotic prescribing for adults with lower respiratory tract infections in primary care, doi.org/10.3389/fmed.2023.1166742


For further information, you can connect with Dr Rogier Hopstaken at rogier.hopstaken@maastrichtuniversity.nl

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