Dr Ricardo Rosales | From Smallpox to Cancer: How Vaccinia Viruses Are Revolutionizing Vaccine Development
About this episode
Vaccines have long been celebrated for their ability to prevent diseases, but some are now being developed to treat existing conditions, such as cancer and viral infections. One promising approach is the use of vaccinia viruses, which were historically used to eradicate smallpox. These vaccines prompt an immune response that can eliminate threats, including cancer cells and cells infected by viruses.
Dr. Ricardo Rosales and his colleagues at VIROLAB are at the forefront of this field, leading innovative research into two vaccinia viruses: MVA and GAB-1. Read More
Original Article Reference
Summary of the papers: ‘Regression of Human Papillomavirus Intraepithelial Lesions Is Induced by MVA E2 Therapeutic Vaccine’, in Human Gene Therapy, doi: 10.1089/hum.2014.024; and ‘MVA E2 therapeutic vaccine for marked reduction in likelihood of recurrence of respiratory papillomatosis’, in Head & Neck., doi: 10.1002/hed.25477; and ‘A recombinant vaccinia virus containing the papilloma E2 protein promotes tumor regression by stimulation macrophage antibody-dependent cytotoxicity’ in Cancer Immunol Immunother, doi: 10.1007/s002620000125.
Contact
For further information, you can connect with Dr Ricardo Rosales at rrosalesvirolab10@gmail.com
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