Dr Matthew Hoare | Understanding Gene Mutations in Chronic Liver Disease

Jun 28, 2023 | biology, health and medicine

About this episode

The liver plays a vital role in keeping us healthy, by controlling levels of sugars and fats in our blood, as well as clearing the blood of toxins. Chronic liver disease affects around 25% of the population and is reported to be the third largest cause of premature death in the UK. Liver disease can occur as the result of long-term consumption of alcohol or viral hepatitis, but the fastest growing cause is non-alcoholic fatty liver disease, associated with obesity and type 2 diabetes. Read More

Original Article Reference

Summary of the papers ‘Somatic mutations and clonal dynamics in healthy and cirrhotic human liver’, in Nature, https://doi.org/10.1038/s41586-019-1670-9; and ‘Convergent somatic mutations in metabolism genes in chronic liver disease’ in Nature, https://doi.org/10.1038/s41586-021-03974-6

Contact

For further information, you can connect with Dr Matthew Hoare at Matthew.Hoare@cruk.cam.ac.uk

This work is licensed under a Creative Commons Attribution 4.0 International LicenseCreative Commons License

What does this mean?

Share: You can copy and redistribute the material in any medium or format

Adapt: You can change, and build upon the material for any purpose, even commercially.

Credit: You must give appropriate credit, provide a link to the license, and indicate if changes were made.

Are you ready to increase the impact of your research?

More episodes

Dr Jörg Enderlein | Building 3D Images of the Biomolecular World

Over the past two decades, advances in super-resolution microscopy have sparked a revolution in imaging: offering...

Niek Lopes Cardozo – Samuel Ward | Is Parallel Development the Key to Accelerating Nuclear Fusion?

The world urgently needs to transition away from fossil fuels to combat climate change. Nuclear fusion – a different...

Professor Nicola Pless – Professor Thomas Maak | How Moral Imagination Can Resolve Corporate Dilemmas

In the face of societal challenges, business leaders are expected to demonstrate responsible leadership and create...

Prof. Diana Jaalouk | Cutting-Edge Cancer Tools: Editing Genes and Cleaning Up Proteins

Cancer continues to challenge scientists and doctors around the world, partly because every tumor is unique and...

Dr. Thomas Tonon | A New Roadmap for Decarbonizing the US Economy

Can existing hydrogen technologies help us achieve net-zero by 2050? Through his research, Dr. Thomas Tonon provides a...

Dr. Mark Dombrovski | From Molecules to Behaviours: Untangling the Principles of Brain Wiring

How does the brain translate what we see into what we do? Every action we take, from catching a ball to avoiding...

Stay Up To Date With SciTube

Subscribe to receive our latest videos straight to your mailbox

 

Follow Us On: