Dr. Ramesh Jha | Creating and Testing Genetic Mutations Efficiently

Jan 29, 2025 | biology, physical sciences

About this episode

From the genes contained in our DNA, the proteins within our bodies are born. As researchers progress in their ability to manipulate DNA, they are beginning to design and create synthetic proteins with a wide array of applications, such as new medical treatments, biofuel production, breakdown of pollutants, and biosensors that can detect specific molecules. To create synthetic proteins with new properties, scientists often need to modify DNA sequences or create entirely new ones. They then need to test the resulting genetic variants to see if they will produce a protein with new functions that could be useful for their desired application. Read More

Original Article Reference

Summary of the paper ‘Targeted mutagenesis and high-throughput screening of diversified gene and promoter libraries for isolating gain-of-function mutations’, https://doi.org/10.3389/fbioe.2023.1202388

Contact

For further information, you can connect with Dr. Ramesh Jha at rjha@lanl.gov

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