Targeting Cancer & Blood Disease 2026
An annual Special Edition bringing together published research animations around a shared research theme.
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Annual Special Edition
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Cancer and blood disorders encompass many different diseases, each driven by complex biological processes and requiring increasingly precise approaches to diagnosis and treatment.
This Special Edition brings together research exploring new ways to understand, detect and treat cancer and blood disease. From targeted therapies and immunotherapy to nanotechnology, drug development and disease biomarkers, the collection highlights research that could contribute to more precise and effective approaches to patient care.
Edition Editor
Dr Nelly Berg
Executive Editor
Professor Jonathan Finlay | Tackling One of the Rarest Childhood Cancers
Imagine a cancer so rare that most doctors will never see a single case in their entire career. Now imagine being the parent of a child diagnosed with it. This is the reality of choroid plexus carcinoma, or CPC – a malignant brain tumour that strikes predominantly in children under the age of four, and one that researchers are only now beginning to truly understand.
Dr Lidia-Maria Mondoc | Revealing the Hidden Link Between Anemia and Blood Cancer Survival Rates
A simple, inexpensive blood test taken at the moment of diagnosis could help predict how long a patient with blood cancer will survive – and potentially open the door to treatments that improve their chances. That is one of the key findings from a study led by Dr Lidia-Maria Mondoc and her colleagues at Lucian Blaga University and the Sibiu County Emergency Clinical Hospital in Romania.
Dr James Kaduk | Mapping a Cancer Drug’s Structure Towards Better Drug Development
Repotrectinib, sold under the brand name Augtyro, is a targeted therapy approved for the treatment of advanced non-small cell lung cancer. Specifically, it blocks a mutated protein called ROS1, which in some patients drives uncontrolled cell growth. It is the kind of precision medicine that has transformed outcomes for certain cancer patients in recent years. Yet until now, the structure of the drug in its pure form had never been reported. That gap has been filled by Dr James Kaduk and colleagues at the International Centre for Diffraction Data.
Marc de la Roche – Maike de la Roche | A New Route to Precision Cancer Immunotherapy
Cancer treatments are increasingly moving beyond one-size-fits-all approaches, and new research led by Marc de la Roche and Maike de la Roche shows how a single biological target could open the door to multiple, more precise immunotherapies. The work focuses on LGR5, a protein found at unusually high levels on the surface of certain cancer cells, including colorectal cancer, liver cancer, and a form of leukaemia.
Dr Fatema Alali | How Ring-Shaped Gold Nanoparticles Could Revolutionise Cancer Treatment
Nanoparticles may be tiny, but their potential impact on medicine is enormous. In a new study, researcher Fatema Alali explores how carefully designed gold nanoparticles could make light-based cancer treatments safer, more precise, and more reliable. Her research focuses on how the shape of these particles controls the way they absorb light and turn it into heat – a key process in photothermal therapy.
The Hidden Role of Platelets: New Insights Towards the Treatment of Aplastic Anaemia
Aplastic anaemia is a common and significant hematologic disease, where the bone marrow cannot produce enough blood cells, leaving people exhausted, prone to infections, and at risk of serious bleeding. Most mechanistic research has focused on how components of the immune system, especially T-cells, mistakenly attack the bone marrow. But new work led by Dr Shuai Tan, Dr Xingmin Feng, and Dr Wanling Sun offers an important shift in perspective: platelets may be doing far more than helping blood clot in aplastic anaemia.
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